About Cygnus Biosciences

Cygnus Biosciences (Beijing) Co., Ltd. is a national high-tech enterprise integrating R&D, conversion, production, and marketing of gene sequencing technology. Founded by Academician Xie Xiaoliang, Professor Huang Yanyi, and Dr. Chen Zitian's team, the company specializes in the research, development, manufacturing, and marketing of gene sequencing instruments, reagents, consumables, and gene testing services. Cygnus is dedicated to providing simpler, more precise, and efficient gene sequencing tools and solutions for various fields in the life sciences, including biological research, medical diagnosis, drug development, animal and plant breeding, customs, disease control, forensic science, and evolutionary research.

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Fluorogenic Sequencing Chemistry

Proprietary fluorogenic sequencing chemistry with high on-off ratio

Simultaneous DNA polymerization, label cleavage and fluorescence generation

One-step chemistry without molecular scars to achieve long read length

Error-correction code (ECC) sequencing

Unique SBS strategy using 3 rounds of dual-base flowgrams combining chemical and information technologies

Four bases encoded in 3 bits with 50% information redundancy

Proprietary ECC algorithm enhances accuracy geometrically

BitSeq Degenerate Sequencing

Two bases areadded in every cycle to eliminate dark cycles

One-round sequencing of M (A/C) and K (G/T) suffices analysis

Turn-around time as low as 6.5 h in BitSeq, 1/3 of conventional methods

Suitable for counting applications such as CNV, NIPT and RNA-seq

AttoSeal Technology

10-18 L Attoliter-Scale Microreactor Array Chip (Attoliter Reactor Array)

AttoSeal Technology 10× Extreme Reagent Savings

LumoSeq Technology

Fluorescence Switching Ratio10000×

No Molecular Scars

Monochromatic fluorescence

Products

GS100 Sequencing Platform

GS100 Sequencing Platform, featuring BitSeq ultra-fast sequencing speed, Q40 standard accuracy, great compatibility, and simple hand-on procedure, is suitable for applications such as NIPT, PGT-A, CNV, mNGS, tNGS, Tumor, etc.

Genetic testing and personalized medication evaluation for hereditary early-onset coronary heart disease

Genetic testing for hereditary early-onset coronary heart disease and individualized medication evaluation is a genetic testing product based on Cygnus sequencer's S100 gene sequencer. It mainly detects genes associated with the risk of early-onset coronary heart disease, including LDLR, LDLRAP1, PCSK9, ABCG5, ABCG8, and APOB. This product is helpful for the early detection and prevention of the disease. Additionally, it also analyzes statin-related genes to evaluate the risk of adverse reactions and the effectiveness of statin drugs

Application Fields

Genetic diseases

Reproductive health

Pathogenic microorganisms

Tumors

Environmental protection

Agricultural breeding

Judicial administration